Mark Behlke: search on Z-Library

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1

Genetic modulation of TLR8 response following bacterial phagocytosis

Michael P. Gantier, Aaron T. Irving, Maria Kaparakis-Liaskos, Dakang Xu, Vanessa A. Evans, Paul U. Cameron, James A. Bourne, Richard L. Ferrero, Matthias John, Mark A. Behlke, Bryan R.G. Williams

Journal:

Year:

2010

Language:

english

File:

PDF, 523 KB

english, 2010

2

Intraperitoneal administration of chitosan/DsiRNA nanoparticles targeting TNFα prevents radiation-induced fibrosis

Isabel Nawroth, Jan Alsner, Mark A. Behlke, Flemming Besenbacher, Jens Overgaard, Kenneth A. Howard, Jørgen Kjems

Journal:

Radiotherapy and Oncology

Year:

2010

Language:

english

File:

PDF, 658 KB

english, 2010

3

A modular platform for targeted RNAi therapeutics

Kedmi, Ranit, Veiga, Nuphar, Ramishetti, Srinivas, Goldsmith, Meir, Rosenblum, Daniel, Dammes, Niels, Hazan-Halevy, Inbal, Nahary, Limor, Leviatan-Ben-Arye, Shani, Harlev, Michael, Behlke, Mark, Benha

Journal:

Nature Nanotechnology

Year:

2018

Language:

english

File:

PDF, 1.92 MB

english, 2018

4

Gene silencing by synthetic U1 Adaptors

Goraczniak, Rafal, Behlke, Mark A, Gunderson, Samuel I

Journal:

Nature Biotechnology

Year:

2009

Language:

english

File:

PDF, 533 KB

english, 2009

5

A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells

Marques, Joao Trindade, Devosse, Thalie, Wang, Die, Zamanian-Daryoush, Maryam, Serbinowski, Paul, Hartmann, Rune, Fujita, Takashi, Behlke, Mark A, Williams, Bryan RG

Journal:

Nature Biotechnology

Year:

2006

Language:

english

File:

PDF, 260 KB

english, 2006

6

RNase H-dependent PCR (rhPCR): improved specificity and single nucleotide polymorphism detection using blocked cleavable primers

Joseph R Dobosy, Scott D Rose, Kristin R Beltz, Susan M Rupp, Kristy M Powers, Mark A Behlke, Joseph A Walder

Journal:

BMC Biotechnology

Year:

2011

Language:

english

File:

PDF, 769 KB

english, 2011

7

Improved Performance of Anti-miRNA Oligonucleotides Using a Novel Non-Nucleotide Modifier

Lennox, Kim A, Owczarzy, Richard, Thomas, Derek M, Walder, Joseph A, Behlke, Mark A

Journal:

Molecular Therapy — Nucleic Acids

Year:

2013

Language:

english

File:

PDF, 1.76 MB

english, 2013

8

Stable expression of shRNAs in human CD34+ progenitor cells can avoid induction of interferon responses to siRNAs in vitro

Robbins, Marjorie A, Li, Mingjie, Leung, Irene, Li, Haitang, Boyer, Doris V, Song, Yong, Behlke, Mark A, Rossi, John J

Journal:

Nature Biotechnology

Year:

2006

Language:

english

File:

PDF, 211 KB

english, 2006

9

CS3-4 Characterisation of microRNA turnover reveals sustained modulation of innate immunity

Michael P. Gantier, Claire E. McCoy, Mark A. Behlke, Bryan R.G. Williams

Journal:

Year:

2010

Language:

english

File:

PDF, 134 KB

english, 2010

10

Chemical Modification of siRNAs for In Vivo Use

Behlke, Mark A.

Journal:

Oligonucleotides

Year:

2008

Language:

english

File:

PDF, 359 KB

english, 2008

11

Self-Assembly into Nanoparticles Is Essential for Receptor Mediated Uptake of Therapeutic Antisense Oligonucleotides

Ezzat, Kariem, Aoki, Yoshitsugu, Koo, Taeyoung, McClorey, Graham, Benner, Leif, Coenen-Stass, Anna, O’Donovan, Liz, Lehto, Taavi, Garcia-Guerra, Antonio, Nordin, Joel, Saleh, Amer F., Behlke, Mark, Mo

Journal:

Year:

2015

Language:

english

File:

PDF, 5.01 MB

english, 2015

12

Nucleotide Bias Observed with a Short SELEX RNA Aptamer Library

Thiel, William H., Bair, Thomas, Wyatt Thiel, Kristina, Dassie, Justin P., Rockey, William M., Howell, Craig A., Liu, Xiuying Y., Dupuy, Adam J., Huang, Lingyan, Owczarzy, Richard, Behlke, Mark A., Mc

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Year:

2011

Language:

english

File:

PDF, 785 KB

english, 2011

13

Noninvasive imaging of Staphylococcus aureus infections with a nuclease-activated probe

Hernandez, Frank J, Huang, Lingyan, Olson, Michael E, Powers, Kristy M, Hernandez, Luiza I, Meyerholz, David K, Thedens, Daniel R, Behlke, Mark A, Horswill, Alexander R, McNamara, James O

Journal:

Nature Medicine

Year:

2014

Language:

english

File:

PDF, 1.06 MB

english, 2014

14

Determinants of Cytokine Induction by Small Interfering RNA in Human Peripheral Blood Mononuclear Cells

Zamanian-Daryoush, Maryam, Marques, Joao T., Gantier, Michael P., Behlke, Mark A., John, Matthias, Rayman, Patricia, Finke, James, Williams, Bryan R.G.

Journal:

Journal of Interferon & Cytokine Research

Year:

2008

Language:

english

File:

PDF, 1.95 MB

english, 2008

15

Engineered transfer RNAs for suppression of premature termination codons

Lueck, John D., Yoon, Jae Seok, Perales-Puchalt, Alfredo, Mackey, Adam L., Infield, Daniel T., Behlke, Mark A., Pope, Marshall R., Weiner, David B., Skach, William R., McCray, Paul B., Ahern, Christop

Journal:

Nature Communications

Year:

2019

Language:

english

File:

PDF, 1.78 MB

english, 2019

16

Alternative splicing of murine T-cell receptor β-chain transcripts

Behlke, Mark A., Loh, Dennis Y.

Journal:

Year:

1986

File:

PDF, 483 KB

1986

17

780. Inhibition of Respiratory Syncytial Virus Gene Expression and Replication by 27mer Dicer Substrate siRNAs

Fischer, Anthony J., Wohlford-Lenane, Christine L., Rose, Scott D., Varga, Steven M., Behlke, Mark A., McCray, Paul B.

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 83 KB

english, 2006

18

Synthesis and characterization of mannosylated pegylated polyethylenimine as a carrier for siRNA

NaJung Kim, Dahai Jiang, Ashley M. Jacobi, Kim A. Lennox, Scott D. Rose, Mark A. Behlke, Aliasger K. Salem

Journal:

International Journal of Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 1.64 MB

english, 2012

19

Evidence That the SRY Protein Is Encoded by a Single Exon on the Human Y Chromosome

Mark A. Behlke, Jonathan S. Bogan, Peggy Beer-Romero, David C. Page

Journal:

Year:

1993

File:

PDF, 276 KB

1993

20

Platelet Activating Factor Receptor Activation Improves siRNA Uptake and RNAi Responses in Well-differentiated Airway Epithelia

Krishnamurthy, Sateesh, Behlke, Mark A, Apicella, Michael A, McCray, Paul B, Davidson, Beverly L

Journal:

Molecular Therapy — Nucleic Acids

Year:

2014

Language:

english

File:

PDF, 695 KB

english, 2014

21

Correlating In Vitro Splice Switching Activity With Systemic In Vivo Delivery Using Novel ZEN-modified Oligonucleotides

Hammond, Suzan M, McClorey, Graham, Nordin, Joel Z, Godfrey, Caroline, Stenler, Sofia, Lennox, Kim A, Smith, CI Edvard, Jacobi, Ashley M, Varela, Miguel A, Lee, Yi, Behlke, Mark A, Wood, Matthew J A,

Journal:

Molecular Therapy — Nucleic Acids

Year:

2014

Language:

english

File:

PDF, 1.43 MB

english, 2014

22

Characterization of Modified Antisense Oligonucleotides in Xenopus laevis Embryos

Lennox, Kim A., Sabel, Jaime L., Johnson, Maegan J., Moreira, Bernardo G., Fletcher, Cherisa A., Rose, Scott D., Behlke, Mark A., Laikhter, Andrei L., Walder, Joseph A., Dagle, John M.

Journal:

Oligonucleotides

Year:

2006

Language:

english

File:

PDF, 7.45 MB

english, 2006

23

Rational Design of Immunostimulatory siRNAs

Gantier, Michael P, Tong, Stephen, Behlke, Mark A, Irving, Aaron T, Lappas, Martha, Nilsson, Ulrika W, Latz, Eicke, McMillan, Nigel AJ, Williams, Bryan RG

Journal:

Molecular Therapy

Year:

2010

Language:

english

File:

PDF, 936 KB

english, 2010

24

Altered Purkinje cell miRNA expression and SCA1 pathogenesis

Rodriguez-Lebron, Edgardo, Liu, Gumei, Keiser, Megan, Behlke, Mark A., Davidson, Beverly L.

Journal:

Neurobiology of Disease

Year:

2013

Language:

english

File:

PDF, 1.10 MB

english, 2013

25

Post-Transcriptional Regulation of Cystic Fibrosis Transmembrane Conductance Regulator Expression and Function by MicroRNAs

Ramachandran, Shyam, Karp, Philip H., Osterhaus, Samantha R., Jiang, Peng, Wohlford-Lenane, Christine, Lennox, Kim A., Jacobi, Ashley M., Praekh, Kal, Rose, Scott D., Behlke, Mark A., Xing, Yi, Welsh,

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2013

Language:

english

File:

PDF, 1.45 MB

english, 2013

26

Manipulation of Cell Physiology Enables Gene Silencing in Well-differentiated Airway Epithelia

Krishnamurthy, Sateesh, Behlke, Mark A, Ramachandran, Shyam, Salem, Aliasger K, McCray Jr, Paul B, Davidson, Beverly L

Journal:

Molecular Therapy — Nucleic Acids

Year:

2012

Language:

english

File:

PDF, 2.56 MB

english, 2012

27

Cleaning Up CRISPR

Behlke, Mark, Jacobi, Ashley

Journal:

Genetic Engineering & Biotechnology News

Year:

2016

Language:

english

File:

PDF, 195 KB

english, 2016

28

Optimizing knockdown of gene expression using the TriFECTa™ Dicer-substrate RNAi reagent system

Rose, Scott D, Collingwood, Michael A, Behlke, Mark A

Journal:

Year:

2006

Language:

english

File:

PDF, 239 KB

english, 2006

29

Rational design and in vitro and in vivo delivery of Dicer substrate siRNA

Amarzguioui, Mohammed, Lundberg, Patric, Cantin, Edouard, Hagstrom, James, Behlke, Mark A, Rossi, John J

Journal:

Nature Protocols

Year:

2006

Language:

english

File:

PDF, 398 KB

english, 2006

30

Small Nucleolar RNAs U32a, U33, and U35a Are Critical Mediators of Metabolic Stress

Carlos I. Michel, Christopher L. Holley, Benjamin S. Scruggs, Rohini Sidhu, Rita T. Brookheart, Laura L. Listenberger, Mark A. Behlke, Daniel S. Ory, Jean E. Schaffer

Journal:

Cell Metabolism

Year:

2011

Language:

english

File:

PDF, 1.15 MB

english, 2011

31

Degradation of Nuclease-Stabilized RNA Oligonucleotides in Mycoplasma-Contaminated Cell Culture Media

Hernandez, Frank J., Stockdale, Katie R., Huang, Lingyan, Horswill, Alexander R., Behlke, Mark A., McNamara, James O.

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Year:

2012

Language:

english

File:

PDF, 568 KB

english, 2012

32

U1 Adaptor Oligonucleotides Targeting BCL2 and GRM1 Suppress Growth of Human Melanoma Xenografts In Vivo

Goraczniak, Rafal, Wall, Brian A, Behlke, Mark A, Lennox, Kim A, Ho, Eric S, Zaphiros, Nikolas H, Jakubowski, Christopher, Patel, Neil R, Zhao, Steven, Magaway, Carlo, Subbie, Stacey A, Jenny Yu, Lume

Journal:

Molecular Therapy — Nucleic Acids

Year:

2013

Language:

english

File:

PDF, 4.03 MB

english, 2013

33

Regulation of Bacteria-Induced Intercellular Adhesion Molecule-1 by CCAAT/Enhancer Binding Proteins

Manzel, Lori J., Chin, Cecilia L., Behlke, Mark A., Look, Dwight C.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2009

Language:

english

File:

PDF, 869 KB

english, 2009

34

RNA Inhibition Highlights Cyclin D1 as a Potential Therapeutic Target for Mantle Cell Lymphoma

Weinstein, Shiri, Emmanuel, Rafi, Jacobi, Ashley M., Abraham, Avigdor, Behlke, Mark A., Sprague, Andrew G., Novobrantseva, Tatiana I., Nagler, Arnon, Peer, Dan, Lewin, Alfred

Journal:

Year:

2012

Language:

english

File:

PDF, 357 KB

english, 2012

35

Highly Efficient CRISPR-Cas9-Based Methods for Generating Deletion Mutations and F0 Embryos that Lack Gene Function in Zebrafish

Hoshijima, Kazuyuki, Jurynec, Michael J., Klatt Shaw, Dana, Jacobi, Ashley M., Behlke, Mark A., Grunwald, David Jonah

Journal:

Developmental Cell

Year:

2019

Language:

english

File:

PDF, 3.09 MB

english, 2019

36

Advances in Molecular and Cellular Therapies for Hearing Loss

Hildebrand, Michael S, Newton, Stephen S, Gubbels, Samuel P, Sheffield, Abraham M, Kochhar, Amit, de Silva, Michelle G, Dahl, Hans-Henrik M, Rose, Scott D, Behlke, Mark A, Smith, Richard JH

Journal:

Molecular Therapy

Year:

2008

Language:

english

File:

PDF, 485 KB

english, 2008

37

Single-molecule detection and tracking of RNA transcripts in living cells using phosphorothioate-optimized 2′-O-methyl RNA molecular beacons

Zhao, Dan, Yang, Yantao, Qu, Na, Chen, Mingming, Ma, Zhao, Krueger, Christopher J., Behlke, Mark A., Chen, Antony K.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.73 MB

english, 2016

38

Respiratory syncytial virus nonstructural protein 2 specifically inhibits type I interferon signal transduction

Murali Ramaswamy, Lei Shi, Steven M. Varga, Sailen Barik, Mark A. Behlke, Dwight C. Look

Journal:

Year:

2006

Language:

english

File:

PDF, 545 KB

english, 2006

39

Real-time Imaging of Single Engineered RNA Transcripts in Living Cells Using Ratiometric Bimolecular Beacons

Song, Yang, Zhang, Xuemei, Huang, Lingyan, Behlke, Mark A., Tsourkas, Andrew

Journal:

Journal of Visualized Experiments

Year:

2014

Language:

english

File:

PDF, 629 KB

english, 2014

40

Tandem Linkage and Unusual RNA Splicing of the T-Cell Receptor β -Chain Variable-Region Genes

Hubert S. Chou, Steven J. Anderson, Marjorie C. Louie, Sandip A. Godambe, Maria Rosa Pozzi, Mark A. Behlke, Konrad Huppi and Dennis Y. Loh

Journal:

Proceedings of the National Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 1.11 MB

english, 1987

41

A Direct Comparison of Anti-microRNA Oligonucleotide Potency

Kim A. Lennox, Mark A. Behlke

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 815 KB

english, 2010

42

Optimal Lipofection Reagent Varies with the Molecular Modifications of the DNA

CONRAD, ABIGAIL H., BEHLKE, MARK A., JAFFREDO, THIERRY, CONRAD, GARY W.

Journal:

Antisense and Nucleic Acid Drug Development

Year:

1998

Language:

english

File:

PDF, 3.60 MB

english, 1998

43

Modified Polyadenylation-Based RT-qPCR Increases Selectivity of Amplification of 3′-MicroRNA Isoforms

Nejad, Charlotte, Pépin, Geneviève, Behlke, Mark A., Gantier, Michael P.

Journal:

Frontiers in Genetics

Year:

2018

Language:

english

File:

PDF, 1.46 MB

english, 2018

44

Evaluation and Reduction of CRISPR Off-Target Cleavage Events

Vakulskas, Christopher A., Behlke, Mark A.

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Year:

2019

Language:

english

File:

PDF, 153 KB

english, 2019

45

Chitosan/siRNA Nanoparticle–mediated TNF-α Knockdown in Peritoneal Macrophages for Anti-inflammatory Treatment in a Murine Arthritis Model

Howard, Kenneth A, Paludan, Søren R, Behlke, Mark A, Besenbacher, Flemming, Deleuran, Bent, Kjems, Jørgen

Journal:

Molecular Therapy

Year:

2009

Language:

english

File:

PDF, 1.45 MB

english, 2009

46

siRNA-induced immunostimulation through TLR7 promotes antitumoral activity against HPV-driven tumors in vivo

Khairuddin, Norliana, Gantier, Michael P, Blake, Stephen J, Wu, Sherry Y, Behlke, Mark A, Williams, Bryan RG, McMillan, Nigel AJ

Journal:

Immunology & Cell Biology

Year:

2012

Language:

english

File:

PDF, 512 KB

english, 2012

47

The Use of CRISPR/Cas9 Gene Editing to Confirm Congenic Contaminations in Host-Pathogen Interaction Studies

Ferrand, Jonathan, Croft, Nathan P., Pépin, Geneviève, Diener, Kerrilyn R., Wu, Di, Mangan, Niamh E., Pedersen, John, Behlke, Mark A., Hayball, John D., Purcell, Anthony W., Ferrero, Richard L., Ganti

Journal:

Frontiers in Cellular and Infection Microbiology

Year:

2018

Language:

english

File:

PDF, 1.73 MB

english, 2018

48

Identification of T-cell receptorVβdeletion mutant mouse strain AU/ssJ (H-2q) which is resistant to collagen-induced arthritis

Tariq M. Haqqi, Subhashis Banerjee, Wendy L. Jones, Gary Anderson, Mark A. Behlke, Dennis Y. Loh, Harvinder S. Luthra, Chella S. David

Journal:

Year:

1989

Language:

english

File:

PDF, 542 KB

english, 1989

49

Development of an siRNA delivery system targeting macrophage function in-vivo

Felix C. Blanco, Priya Srinivasan, Ryan M. Walk, Jason A. Snyder, Mark Behlke, Aliasger K. Salem, Stanislav Vukmanovic, Anthony D. Sandler

Journal:

Journal of the American College of Surgeons

Year:

2012

Language:

english

File:

PDF, 58 KB

english, 2012

50

Assessing the Sensitivity of Commercially Available Fluorophores to the Intracellular Environment

Chen, Antony K., Cheng, Zhiliang, Behlke, Mark A., Tsourkas, Andrew

Journal:

Analytical Chemistry

Year:

2008

Language:

english

File:

PDF, 468 KB

english, 2008

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